The Judas Strain (Sigma Force 4)

Lisa continued while he worked, pacing at the foot of the bed. "No organism is evil for the sake of being evil. Not even a virus. There has to be a purpose to its toxification of bacteria. Considering the broad spectrum of bacteria it converts, it can't be random chance. So 1 wondered: What does it gain by doing so?"

Devesh nodded, urging her to continue. But plainly her conclusions were not anything new. He was continuing to test her.

Lisa stared at the patient. "What does it gain? It gains access to forbidden territory: the human brain. Dr. Barnhardt mentioned how ninety percent of the cells that make up our body are nonhuman. Mostly bacterial cells. One of the few places that remain off-limits to viral or bacterial infections is our skulls. Our brains are protected against infection, kept sterile. Our bodies have developed an almost impenetrable blood-brain barrier. A filter that lets blood's oxygen and nutrients reach the brain, but little else."

"So if something wanted to get inside our skulls . . . ?" Devesh prompted.

"It would take a major assault to bridge the blood-brain barrier. Like turning our own bacteria against us, to weaken the body enough that the virus could slip through the barrier and into the brain's fluid. That's the biologic advantage gained by the virus when it turns bacteria toxic."

"You do amaze," Devesh said. "I knew there was a reason to keep you alive."

Despite the compliment buried in there, Lisa drew little comfort at the implied threat.

"So the ultimate question is why," Devesh continued. "Why does the virus want to get inside our heads?"

"Liver fluke," Lisa said.

The non sequitur was strange enough to finally regain Devesh's full attention. "Come again?"

"Liver flukes are an example of nature's determination. Most flukes have a life cycle that involve three hosts. The human liver fluke produces eggs that pass out of the body in feces, which are then washed into sewers or waterways and consumed by snails. The eggs then hatch into little worms that drill out of the snail and seek out their next host: some passing fish. The fish is then caught, consumed by humans, where the worm travels to the liver, and grows into an adult fluke, where it lives happily ever after."

"Your point being?"

"The Judas Strain may be doing something along this line. Especially if you consider the Lancet liver fluke. Dicrocoelium dendriticum. It also uses three hosts: cattle, snail, and ant. But what it does in the ant stage is what I find most intriguing."

"And that is?"

"Inside the ant, the fluke controls the insect's nerve centers, changes its behavior. Specifically, whenever the sun sets, the fluke compels the ant to climb a blade of grass, lock its mandible, and wait to be eaten by a grazing cow. If not eaten, the ant returns to its nest at sunrise—only to repeat the same thing again the next night. The fluke literally drives the ant like its own little car."

"And you think the virus is doing that?" Devesh said.

"Possibly in some manner. But I mostly bring this up to remind you how insidious nature can be in finding territory to exploit. And the brain, sterile and off-limits, is certainly virgin territory. Nature will try to exploit it, like the fluke with the ant."

"Brilliant. Definitely an angle to pursue. But there may be a fly in that particular ointment." Devesh returned to the computer. He had been uploading a Quicktime video. "I mentioned that the virus has been penetrating into the cerebrospinal fluid of all the patients that survived the initial bacterial assault. Here is what happens when it does."

He clicked the play button.

A silent video began to run. Two white-smocked men struggled to strap down a writhing naked man, his head shaved, wires running from electrodes attached to skull and chest. He fought, snarling and frothing. Though he was plainly debilitated, with sores and blackened boils, one arm ripped free of the tied cuffs. A clawed hand raked one of the restrainers. The patient then reared up and bit deep into the same man's forearm.

The video ended.

Devesh switched off the monitor. "We're already getting reports of similar manic responses from some of the patients, those earliest exposed."

"It could be another form of catatonia. Catatonic stupor is just one form." Lisa nodded to the patient in the bed. "But there is also an opposite reaction, its mirror image: catatonic excitement. Characterized by extreme hyperactivity, severe facial grimaces, animal-like shrieks, and psychotic violence."

Devesh stood and turned back to the hospital bed. "Two sides of the same coin," he mumbled, and studied the prone woman.

"The man in the video," Lisa asked. She had noted the background in the video. The film had not been taken aboard the cruise ship. "Who was he?"

Devesh nodded sadly toward the bed. "Her husband."

Lisa tensed at the revelation. She stared at the woman sprawled on the bed. Her husband. . .

"The pair were exposed at the same time," Devesh said. "Found on a yacht that had become grounded on a reef near Christmas Island. Your John Doe below, with the flesh-eating disease, must have swum to shore. We recovered these two, still aboard the yacht. Too weak, near to death."

So that was how the Guild first learned about all this.

Devesh nodded to the woman. "Which of course begs the question Why did her husband have a complete schizoid breakdown, while our patient here is on the way to healing her external wounds and remains happily complacent and catatonic? We believe a possible cure for everyone lies in that answer."

Lisa did not argue. She was no fool. Despite what Devesh claimed, Lisa knew the Guild's operation was not motivated by altruistic reasons. Their search for a cure was not to save the world. They had plans for this virus, but before they could utilize it, they needed to fully understand it. To develop an antidote or cure. And in this regard, Lisa was not at cross-purposes with the Guild. A cure needed to be discovered. The only question: How to find it without the Guild's knowledge?

Devesh turned on a heel and headed toward the door. "You've made excellent progress, Dr. Cummings. I commend you. But tomorrow is another day. And we'll need more progress." He glanced back at her, one eyebrow raised. "Is that understood?"

She nodded.

"Most excellent." He paused again. "Oh, and our cruise ship's esteemed owner, Sir Ryder Blunt, has invited everyone for afternoon cocktails in his suite. A small celebration."

"Celebration for what?"

"A welcome as we come into port," Devesh explained, gathering up his cane. "We're almost home."